Issue

Commentary

01 January 2001

(1)A lysosomal proteaase enters the death scene

(2)Endothelium-derived free radicals: for worse and for better

(3)Breaching the mucosal barrier by stealth: an emerging pathogenic mechanism for enteroadherent baterial pathogens

(4)Petulant cellular acts: destroying the ECM rather than creating it

(5)The tolerent recipient: looking great in someone else's genes

Volume 107(2)

Januray 15 2001

(1)Sarcoglycan, the heart, and skeletal muscles: new treatment, old drug?

(2)Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse

(3)More than the sum of the parts: cooperation between leukocyte adhesion receptors during extravasation

(4)Hypertrophy and hyperfunction of the diabetic kidney

Volume 107(3)

February 1 2001

(1)Corticosteroids,IgE and atopy

(2)Mother-to-infant transmission of HIV-1: the placenta fights back

(3)Local and systemic control of the osteoblast

(4)HIV versus the immune system: another apparent victory for the virus

Volume 107(4)

February 15 2001

(1)The proper study of mankind

(2)Chondrogenesis just ain't what it used to be

Volume 107(5)

March 1 2001

(1)MHC class II genotype and the control of viremia in HIV-1 infected individuals on highly active antiretroviral therpay

(2)How much help does a vaccine-induced T-cell response need?

Volume 107(6)

March 15 2001

(1)Homocysteine: a sulph'rous fire

(2)Pathogenesis of hemangioma

(3)The SAMP1/Yit mouse: another step closer to modeling human inflammatory bowel disease

(4)Conserved response to oxygen deprivation

Volume 107(7)

April 1 2001

(1)Chemokines: the times they are a-changin'

(2)Imprints of disease at GNSA1

(3)DR,DQ,and you: MHC alleles and autoimmunity

(4)Routes to allograft survival

(5)Transition metals redox: reviving an old plot for diabetic vascular disease

Volume 107(8)

April 15 2001

(1)Inefction,mimics, and autoimmune disease

(2)More weapons in the arsenal against ischemic retinopathy

(3)�-adrenergic receptors in the failing heart: the good,the bad, and the unknown

Volume 107(9)

May 1 2001

(1)The case of CO signaling: why the jury is still out

(2)A TWIST in the fate of human osteobalsts identifies signaling molecules involved in skull development

(3)Cycling with the parathyroid

(4)Cytokines and cellular interactions in inflammatory synovitis

Volume 107(10)

May 15 2001

(1)VCAM-1 is critical in atherosclerosis

(2)Insulin resistance and the disruption of Glut4 trafficking in skeletal msucle

(3)Can VEGF reverse diabetic neuropathy in human subjects?

(4)Osteolysis and cancer

(5)Hyperhomocysteinemia and the funtion of endoplasmic reticulum

(6)A role for calreticulin in the adult heart?

Volume 107(11)

1 June 2001

(1)Gene therapy for rheumatoid arthritis?

(2)Not the usual suspects: the unexpected sources of tissue regeneration

15 June 2001

(2)Integrin-associated protein(CD47): an unusual activator of G protein signaling

(3)Plumonary fibrosis: a cellular overreaction or failure of communication?

(4)ADP and platelets:the end of the beginning

(5)TNF and receptors in organ-specific autoimmune disease: multi-layerd functioning mirrored in animal models

1 July 2001

(2)The multiple contributions of thyroid hormone to heat production

(3)Regulation of hypoxia-induced angiogenesis: a chaperone escorts VEGF to the dance

15 July 2001

(1)The potential of signal transduction inhibitors for the treatment of arthritis: is it all just JNK?

(2)New functions for the NHERF family of proteins

(3)Cholangiocytes and primary biliary cirrhosis: prediction and predication

1 August 2001

(2)Statins' benefits begin to sprout

(3)Advances in hepatocyte transplantation

15 August 2001

(2)Ferroprotein mutation in autosomal dominant hemachormatosis: loss of function, gain in understanding

(3)TGF-�/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammation

1 September 2001

(2)Peripheral prion pursuit

(3)An experiment of nature: 1-arginine deficiency and NO insufficiency

(4)An alternative lifestyle for immortalized oral keratinocytes

15 September 2001

(2)Are the natural killer cells  key to treating Epstein-Barr virus-associated lymphoproliferative diseases?

(3)VacA pores as portable portals for urea

(4)Exploring pathways for memory T cell generation

1 October 2001

(2)The Survivin saga goes on in vivo

15 October 2001

(2)Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension

1 November 2001

(2)Chemokines and atherosclerosis: what Adam Smith has to say about vascular disease

(3)Is it time to modify the reverse cholesterol transport model?

(4)Targetting aberrant transcriptional repression in leukemia: a therapeutic reality

(5)Guanine nucleotides and acute renal failure

15 November 2001

(2)More sweetness than light?-A search for the causes of diabetic vasculopathy

1 December 2001

(2)It infects me,it infects me not:phenotypic siwthcing in the fungal pathogen Cryptococcus neofromans

(3)The clinical relevance of glycobiology

(4)Caught flat-footed:podocyte damage and molecular bases of focal glomerulosclerosis

15 December 2001

(1)Turning on LIGHT

(2)Choosing sides in the battle against gastric acid

(3)Putting the brakes on arthritis:can suppressors of cytokine signalling(SOCS) suppress rheumatoid arthritis?